Abstract
This paper contributes to the recent debate between two important streams within current economic geography and regional studies: global value chains/global production networks theories, and regional innovation system theory. Based on the review of key literature, the authors first identify the key conceptual differences between these two streams and then provide a comparative overview of their policy implications. Thereafter, the authors show that considerable space for mutual inspiration in conceptual as well as policy terms exists, especially between the notions of strategic coupling and the new path development model. Moreover, the authors suggest six additional arenas of mutual conceptual and policy-relevant inspiration between these two streams as avenues for future research.