Abstract
We identify two immediate goals in health promotion. Firstly, in rather short term basis, to achieve extensive adoption of integrated care services supported by information and communication technologies (ICT). A second aim is to define proper strategies towards future developments in Personalized Health based on the interplay between emerging Systems Medicine and new, but robust, technological developments. In the article, we review the challenge of current healthcare systems. Also, the trends at different levels (new health paradigm, organizational aspects, technological components, etc.) are identified. We conclude that multilevel systems integration constitutes a pivotal common element to shape the new health scenario for the 21st Century, and that open platforms and standards are needed to support the integration.