The project is divided into eight Work Packages (WPs), whereby WP-1 to WP-5 covers the realization of the principle aim of PROMYSE of establishing methylotrophic cell factories for the conversion of methanol to value-added products. WP-6 and WP-7 on the other side will deal with the demonstration of industrial relevance and dissemination, while WP-8 deals with the management of the PROMYSE project.